Libuše comes from an artistic family. She studied photography at Prague’s FAMU. For four years, she’s worked in an intaglio print shop in Prague’s Smíchov district, where she created her first major documentary series, Night Shift. At the end of the 1970s, she traveled to Japan and returned twice more afterward. For a long time, she documented the Roma and Vietnamese community in normalized Czechoslovakia and also the Prague T-Club, which focused on the queer minority. After 1985, she legally moved to West Berlin, took up residence in the Turkish district of Kreuzberg, and spent her first years working as a domestic worker. After returning to Czechoslovakia, she began teaching photography at the Secondary Industrial School of Graphic Arts on Hellichova Street in Prague, where she worked until recently. In 2017, she published a comprehensive monograph, Black Years (wo men Publishing House), a cross between a literary diary and a photographic book.
Furthermore, in 2019, she celebrated great success with her solo exhibition Evokativ and the book of the same name (untitled publishing house). Evokativ became the leading exhibition of the prestigious photography festival Les Rencontres d’Arles 2019. The Guardian honored it by naming it the most distinguished photography exhibition of the year. Since 2023, Libuše has been the Head of the Photography Department at the Faculty of Art and Design in Pilsen.